Angioid streaks, clinical course, complications, and current therapeutic management

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Angioid streaks, clinical course, complications, and current therapeutic management

Angioid streaks are visible irregular crack-like dehiscences in Bruch's membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget's disease, sickle-cell anemia, acromegaly, Ehlers-Danlos syndrome, and diabetes mellitus, but also appear in patients without any systemic disease. Pat...

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Angioid streaks and elastorrhexis.

ANGIOID streaks are thought to be due to breaks in the elastic lamina of Bruch's membrane. Ophthalmoscopically they present a jagged peripapillary ring which may be incomplete and from which radiate irregular spokes of width similar to retinal vessels. With time, they may progress, or become less distinct. Their colour varies from reddish-brown to dark brown according to the density of the over...

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Angioid Streaks in Psuedoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a hereditary disorder that affects primarily the elastic tissues of skin, eyes and blood vessels. Its estimated prevalence is thought to be 1:25,000 100,000. PXE patients also carry an increased risk for cardiovascular and gastrointestinal diseases. Early diagnosis can play a crucial role in preventing early loss of vision and systemic complications in these pa...

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Classification of angioid streaks.

ANGIOID streaks of the retina were first described by Doyne (1889). They have since been the subject of much controversy. More than 200 cases have been reported in the literature, but histological studies have been few and the changes described have varied. The condition is frequently associated with pseudoxanthoma elasticum, with cardiovascular disease, and with Paget's disease of bone. A simi...

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Angioid streaks of the retina.

A table of the optical power of obliquely crossed cylinders, and the implications of oblique cylinder ideas for retinoscopy with cylinders are presented. The basis of streak-retinoscopy is a band-like retinal image of the immediate source of light, which can be rotated in the principal meridians of astigmatism. Similarities exist between cylinder-retinoscopy and streak-retinoscopy as regards as...

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ژورنال

عنوان ژورنال: Therapeutics and Clinical Risk Management

سال: 2008

ISSN: 1178-203X

DOI: 10.2147/tcrm.s4682